Predictive factors for the development of rubeosis following proton beam radiotherapy for uveal melanoma

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Predictive factors for the development of rubeosis following proton beam radiotherapy for uveal melanoma.

AIMS/BACKGROUND Proton beam radiotherapy can effectively treat primary uveal melanomas of any size. Some patients, however, develop adverse late effects following treatment and the purpose of this study was to determine which factors give rise to a poor local outcome. METHODS The hospital records from a first cohort of 127 patients treated by protons from 1989 to 1992 were reviewed retrospect...

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Intraocular inflammation after proton beam irradiation for uveal melanoma.

AIM To describe the inflammatory reaction that can occur following proton beam irradiation of uveal melanomas based on a large series of patients and to try to determine the risk factors for this reaction. METHODS Data from a cohort of patients with uveal melanoma treated by proton beam irradiation between 1991 and 1994 were analysed. The presence of inflammation was recorded and evaluated. K...

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A new model for Spread Out Bragg Peak in proton therapy of uveal melanoma

In this research, in order to improve our calculations in treatment planning for proton radiotherapy of ocular melanoma, we improved our human eye phantom planning system in GEANT4 toolkit. Different analytical models have investigated the creating of Spread Out Bragg Peak (SOBP) in the tumor area. Bortfeld’s model is one of the most important analytical methods. Using convolution method, a new...

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Proton beam radiotherapy in the management of uveal melanoma: Clinical experience in Scotland

AIM To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland. METHODS A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994-2005). Data obtained included: gender, past ocular/medical history, age, presenting complaint(s), diagnosis, laterality, tumor location/ultrasound characteristics, visual acuity (VA) and intraocul...

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performed. Previous cases of vitelliform retinopathy have had some clinical findings consistent with MAR, while others have not. None of these reports had clinical evidence of choroidal involvement. The vitelliform lesions have been postulated to represent a new paraneoplastic clinical manifestation. The pathologic results in this case argue against a paraneoplastic entity but may suggest a loc...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1997

ISSN: 0007-1161

DOI: 10.1136/bjo.81.9.748